R106 - R6 673


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Bioneem is an emulsifiable concentrate derived from natural plant origin, through cold press extraction, for the control of various sucking, chewing and biting insects including bollworm, codling moth, spider mites, snout beetle, fruit fly and aphids on a range of crops.

Mode of action

Bioneem has multiple modes of action against a range of sucking, chewing and biting insect pests. Bioneem affects growth, development, behaviour, reproduction and metamorphosis in a diverse insect taxa. Ingestion of Bioneem interferes with the growth and molting process of insects by disrupting the synthesis of the ecdysone hormone thereby disrupting the insect’s molting process so that the immature larvae cannot develop into adults. After treatment with Bioneem, you may find insects with crippled, distorted wings or the immature larvae and nymphs remain in an immature stage and then die.

Applications of Bioneem also lead to anti-feedancy and starvation through the stimulation of deterrent cells within the insects’ chemoreceptors and by blocking the feeding stimulation in insects by firing the “sugar” receptor cells.

3g/ℓ Azadirachtin. The active ingredient in Bioneem, azadirachtin, is an environmentally-friendly product, which is derived from neem seed kernels which contain a range of triterpenoids including azadirachtin.



  • Bioneem is used to control a wide range of insects (up to 200 insect types) including white flies, leafminers, mealybug, thrips, fruit flies, leaf hopper, red spider mite, weevils and many more.
  • Bioneem has a number of different modes of action and therefore it is less likely that insects will develop resistance as compared to single mode of action chemicals.
  • Bioneem is highly compatible with an integrated pest management (IPM) approach. Bioneem has been found to be compatible with common fungicides, insecticides and fertilizers being used.
  • Azadirachtin is relatively harmless to insects that pollinate crops and trees, such as butterflies, spiders and bees; ladybugs that consume aphids; and wasps that act as a parasite on various crop pests. This is because neem products must be ingested to be effective. Thus, insects that feed on plant tissue succumb, while those that feed on nectar or other insects rarely contact significant concentrations of neem products.
  • Non-target organisms - No toxic endpoints have been identified for non-target birds, non-target plants, and non-target soil organisms such as earthworms.

Use of beneficial organisms

Bioneem is the ideal complement to beneficial insect use. Studies have found that there are few effects on insect predators and parasitoids because Bioneem is only harmful when ingested. Bioneem does not persist in the environment at high
temperatures, ultraviolet light and rainfall can degrade the active ingredient. Bioneem can be used in growing systems where beneficial insects have been released.

There are no concerns for any non-target organisms when Bioneem is applied in accordance with approved label use directions. No toxic endpoints have been identified for non-target birds, non-target plants, and non-target soil organisms such as earthworms.

Beneficial Predator's: Such as ladybugs that consume aphids and wasps that act as a parasite on various crop pests. The bioneem needs to be consumed from the tissue of the leaves - so only insects that "attack/consume" plants will be effected. 

Bees: Honey bees and other pollinators that feed on nectar, and predators of insect pests are unlikely to consume sufficient quantities of Bioneem to cause adverse effects.

Water: Under approved conditions of use, calculated Risk Quotients (RQs) for fish and aquatic invertebrates are well below any Levels of Concern (LOCs) for threatened and endangered species.


How it works

The key insecticidal ingredient found in the neem tree is Azadirachtin, which is a naturally occurring substance that belongs to an organic molecule class called tetranortriterpenoids.

This substance is structurally similar to insect hormones called ‘ecdysones’ which control the process of metamorphosis as the insects pass from larva to pupa to adult. The process of metamorphosis requires the careful synchrony of many hormones and other physiological changes to be successful.

Azadirachtin is an ‘ecdysone blocker’ that blocks the insect’s production and release of these vital hormones. Insects then will not breed, thus breaking their life cycle.

Azadirachtin also serves as a feeding deterrent for some insects. Depending on the stage of life-cycle, insect death may not occur for several days. However, upon ingestion of small quantities, insects become quiescent and stop feeding. Residual insecticidal activity is evident for up to seven days or longer, depending on insects and application rate.


How to use


  • Application rates vary between 30 mℓ  - 50 mℓ per 10 ℓ of water, depending on the growth stage of plant and level of infestation. This equates to 6 mℓ - 10 mℓ per 2 ℓ of water.
  • Per HA use 2-4ℓ (Use higher dosage under high insect pressure).


  • Use a Compression Sprayer with a fine mist setting to generously distribute the Bioneem solution over the plant canopy or affected areas.
  • Apply as a full cover spray ensuring thorough wetting of the crop on both sides of the leaf surface. Do not spray past the point of run-off.

Advanced Directions:

  • Spray applications should be preventative: Bioneem is most effective when applied in a preventative program with sprays every 7 days. Under high insect pressure apply every 3-4 days in order to break the pest life cycle. After two sprays, monitor insect pressure and adjust spray up to 14 day intervals, or as necessary.
  • Spray in combinations: Bioneem can be used as a stand-alone product, however for increased overall efficacy and effectiveness against adult insect life stages it can be combined with biopesticides or chemicals.
  • Timing of applications: For best results spray in the early to mid morning or late afternoon when temperatures are cool. Do not apply in temperatures above 30°C.
  • Plant compatibility: Extensive testing has shown that most plants show no sign of phytotoxicity to Bioneem. However, if unsure about plant phytotoxicity, a test spray on a few plants, or few leaves, prior to treating the whole area, is recommended. Bioneem may cause damage to sensitive flowers. Do not apply in temperatures above 30°C.
  • Regular scouting: Helps to ensure the early detection of immature stages of insects and allows for the best timing of applications.

Bioneem is an insect growth regulator and is mostly effective against the immature stages of insects, therefore repeated applications may be needed to achieve the desired result. Bioneem does not cause an immediate knockdown after application, it normally takes 3-7 days for death to occur. However, damage is reduced almost immediately due to the antifeedant effect of the product.



  • Contains Azadirachtin (1500ppm-3000ppm).
  • Certified organic by Ecocert
  • Reg. No. L6958 Act No. 36 of 1947
  • Neem products are recognized in organic guidelines by IFOAM.


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